Short-Term Diet Restriction but Not Alternate Day Fasting Prevents Cisplatin-Induced Nephrotoxicity in Mice
نویسندگان
چکیده
منابع مشابه
Effect of Short-Term Modified Alternate-Day Fasting on the Lipid Metabolism in Obese Women
OBJECTIVE: Obesity is a worldwide health problem, with increasing prevalence associated with an increased risk of chronic diseases. Decrease in energy intake has been shown to lower the risk of coronary artery disease (CAD) in obese. The common form of dietary restriction is daily calorie restriction (CR). Another form is alternate-day fasting (ADF). The ability of modified ADF to facilitate we...
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The preventive effect of Thea sinensis melanin (TSM) against cisplatin-induced nephrotoxicity was studied on ICR mice. Animals were given 20mg/kg i.p. of cisplatin, and TSM was injected i.p. in doses 10-40 mg/kg 2h before intoxication. The protective effects were evidenced by a complete inhibition of the cisplatin-induced elevation of serum Blood Urea nitrogen (BUN), prevention of oxidative str...
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Cisplatin is an effective anticancer drug; however, cisplatin use often leads to nephrotoxicity, which limits its clinical effectiveness. In this study, we determined the effect of dichloroacetate, a novel anticancer agent, in a mouse model of cisplatin-induced AKI. Pretreatment with dichloroacetate significantly attenuated the cisplatin-induced increase in BUN and serum creatinine levels, rena...
متن کاملThe Effect of Short‐Term Periodic Fasting on the Acetaminophen-Induced Liver Injury in Mice
Introduction: In many cultures fasting is recommended as a way to protect and promote health. However, there are few studies on the effects of fasting on organ function and resistance to toxic agents such as drugs. This study was conducted to investigate the effect of short-term periodic fasting on the acetaminophen hepatotoxic effects in mice. Methods: In this...
متن کاملeffect of short-term modified alternate-day fasting on the lipid metabolism in obese women
objective: obesity is a worldwide health problem, with increasing prevalence associated with an increased risk of chronic diseases. decrease in energy intake has been shown to lower the risk of coronary artery disease (cad) in obese. the common form of dietary restriction is daily calorie restriction (cr). another form is alternate-day fasting (adf). the ability of modified adf to facilitate we...
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ژورنال
عنوان ژورنال: Biomedicines
سال: 2020
ISSN: 2227-9059
DOI: 10.3390/biomedicines8020023